Acrosin rabbit pAb
Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
ACR; ACRS; Acrosin
UniProt
P10323
Swiss Prot
P10323
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from Acrosin . at AA range: 40-120
Target
Acrosin
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
45kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
45kD
Fragment
IgG
Subcellular Location
Acrosomal vesicle, extracellular region, nucleus, Golgi-associated vesicle, acrosomal matrix, protein complex
Other Product Names
ACR; ACRS; Acrosin
Gene ID (Human)
49
Available Sizes
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