Bmi-1 (F270) Rabbit pAb
Bmi1 is a component of the PRC1 complex, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit . Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16 INK4A and p19 ARF genes and is required for maintenance of adult hematopoietic and neural stem cells .
Product Specifications
Background
Product Name Alternative
PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51
UniProt
P35226
Swiss Prot
P35226
Reactivity
Human
Immunogen
Recombinant Protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1mg/mL
Dilution
WB 1:1,000-2,000
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
37-43kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
37-43kDa
Fragment
IgG
Subcellular Location
Cytoplasm, Nucleus
Other Product Names
PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51
Gene ID (Human)
100532731
Available Sizes
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