Bmi-1 (F270) Rabbit pAb
Bmi1 is a component of the PRC1 complex, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit . Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16 INK4A and p19 ARF genes and is required for maintenance of adult hematopoietic and neural stem cells .
Product Specifications
Background
Synonyms
PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51
Gene ID
100532731
UniProt
P35226
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Species Reactivity
Human
Reactivity
Human
Immunogen
Recombinant Protein
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Concentration
1 mg/mL
Dilution
WB 1:1,000-2,000
Molecular Weight
37-43kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/EA363-1.pdf
Observed Molecular Weight
37 - 43 kDa
Subcellular Location
Cytoplasm, Nucleus
Other Product Names
PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51
Gene ID (Human)
100532731
SwissProt (Human)
P35226
Available Sizes
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