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ATG13 Rabbit pAb

Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.

Product Specifications

Background

Atg13 was identified as a constitutively expressed protein that was genetically linked to Atg1/Apg1, a protein kinase required for autophagy. Overexpression of Atg1 suppresses the defects in autophagy observed in Atg13 mutants. Autophagy requires a direct association between Atg1 and Atg13, and is inhibited by TOR-dependent phosphorylation of Atg13 under high-nutrient conditions.

Synonyms

KIAA0652,  Apg13, Autophagy-related protein 13 antibody

Gene ID

9776

UniProt

O75143

Cellular Locus

Cytoplasm

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IHC

Validated Applications

IHC

Stability

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Concentration

1 mg/mL

Dilution

IHC 1:100-200

Molecular Weight

57kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/EA353-1.pdf

Observed Molecular Weight

57 kDa

Subcellular Location

Cytoplasm

Other Product Names

KIAA0652, Apg13, Autophagy-related protein 13 antibody

Gene ID (Human)

9776

SwissProt (Human)

O75143

Available Sizes

Curated Selection

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