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ATG5 Rabbit pAb

Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.

Product Specifications

Background

Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.

Synonyms

APG5, APG5L, ASP, Autophage Cysteine protein5 antibody

Gene ID

9494

UniProt

Q9H1Y0

Cellular Locus

Cytoplasm, Membrane

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IHC

Validated Applications

IHC

Stability

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Concentration

1 mg/mL

Dilution

IHC 1:100-200

Molecular Weight

32kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/EA350-1.pdf

Observed Molecular Weight

32 kDa

Subcellular Location

Cytoplasm, Membrane

Other Product Names

APG5, APG5L, ASP, Autophage Cysteine protein5 antibody

Gene ID (Human)

9494

SwissProt (Human)

Q9H1Y0

Available Sizes

Curated Selection

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