ATG4a Rabbit pAb
Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Control of autophagy was largely discovered in yeast and involves proteins encoded by a set of autophagy-related genes (Atg). Formation of autophagic vesicles requires a pair of essential ubiquitin-like conjugation systems, Atg12-Atg5 and Atg8-phosphatidylethanolamine (Atg8-PE), which are widely conserved in eukaryotes. Numerous mammalian counterparts to yeast Atg proteins have been described, including three Atg8 proteins (GATE-16, GABARAP, and LC3) and four Atg4 homologs (Atg4A/autophagin-2, Atg4B/autophagin-1, Atg4C/autophagin-3, and Atg4D/autophagin-4).
Product Specifications
Background
Synonyms
Apg4a, Atg4al, Autl2, Cysteine protease ATG4A antibody
Gene ID
115201
UniProt
Q8WYN0
Cellular Locus
Cytoplasm
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Protein
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
IHC
Validated Applications
IHC
Stability
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Concentration
1 mg/mL
Dilution
IHC 1:100-200
Molecular Weight
45kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/EA347-1.pdf
Observed Molecular Weight
45 kDa
Subcellular Location
Cytoplasm
Other Product Names
Apg4a, Atg4al, Autl2, Cysteine protease ATG4A antibody
Gene ID (Human)
115201
SwissProt (Human)
Q8WYN0
Available Sizes
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