MEK3 Rabbit pAb
Three alternatively spliced transcript variants of MEK3 encoding distinct isoforms have been reported. Isoform B utilizes a different start codon compared to isoform C resulting in the production of a N-terminal segment of isoform B which is shorter and distinct from isoform C . MEK3b is the predominant form of MEK3 and strongly activates p38 MAP kinase .
Product Specifications
Background
Synonyms
MAP2K3; MKK3; PRKMK3; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPKK3; MAPK/ERK kinase 3
Gene ID
5606
UniProt
P46734
Cellular Locus
Cytosol,Nucleus
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Protein
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
IHC
Validated Applications
IHC
Stability
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Concentration
1 mg/mL
Dilution
IHC 1:100-200
Molecular Weight
34,39kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/EA345-1.pdf
Observed Molecular Weight
34,39 kDa
Subcellular Location
Cytosol, Nucleus
Other Product Names
MAP2K3; MKK3; PRKMK3; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPKK3; MAPK/ERK kinase 3
Gene ID (Human)
5606
SwissProt (Human)
P46734
Available Sizes
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