Sumarotene
Sumarotene (Ro 14-9706), an arotinoid methyl sulfone, is a potent dermatologic agent for the repair of photodamage, antikeratinization, and antiproliferation. Sumarotene exhibits in rats a prolactin-suppressive activity which affects lactation[1][2].
Product Specifications
CAS Number
105687-93-2
Product Name Alternative
Ro 14-9706
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sumarotene.html
Smiles
CC1(C2=CC(/C(C)=C/C3=CC=C(C=C3)S(C)(=O)=O)=CC=C2C(C)(CC1)C)C
Molecular Formula
C24H30O2S
Molecular Weight
382.56
References & Citations
[1]J Misiewicz, et al. Topical treatment of multiple actinic keratoses of the face with arotinoid methyl sulfone (Ro 14-9706) cream versus tretinoin cream: a double-blind, comparative study. J Am Acad Dermatol. 1991 Mar;24 (3) :448-51. |[2]A Edelmann, et al. Prolactin lowering activity of the retinoid Ro 14-9706 affecting lactation and pup survival. Arch Toxicol. 1994;68 (6) :385-93.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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