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ERK1/2 Rabbit pAb

Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.

Product Specifications

Background

Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.

Synonyms

MAPK, Mitogen-activated protein Kinase, PRKM2, MK01

Gene ID

5594/5595

UniProt

P27361/P28482

Cellular Locus

Nucleus

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC

Validated Applications

WB,IHC

Stability

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Concentration

1 mg/mL

Dilution

WB 1:1,000-2,000 IHC 1:50-100

Molecular Weight

44,42kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/EA331-1.pdf

Observed Molecular Weight

44,42 kDa

Subcellular Location

Nucleus

Other Product Names

MAPK, Mitogen-activated protein Kinase, PRKM2, MK01

Gene ID (Human)

5594/5595

SwissProt (Human)

P27361/P28482

Available Sizes

Curated Selection

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