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KChIP1 Rabbit pAb

Human K (v) channel interacting protein 1 (KCHIP1) is a new member of the neural calcium binding protein superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. KChIP1 is a neuronal calcium sensor protein that is predominantly expressed at GABAergic synapses and it has been related with modulation of K (+) channels, GABAergic transmission and cell death.

Product Specifications

Background

Human K (v) channel interacting protein 1 (KCHIP1) is a new member of the neural calcium binding protein superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. KChIP1 is a neuronal calcium sensor protein that is predominantly expressed at GABAergic synapses and it has been related with modulation of K (+) channels, GABAergic transmission and cell death.

Product Name Alternative

KCNIP1, MGC9, MGC95, A type potassium channel modulatory protein 1

UniProt

Q9NZI2

Swiss Prot

Q9NZI2

Reactivity

Human, Mouse

Immunogen

Synthetic Peptide

Clonality

Polyclonal

Source

Rabbit

Applications

IHC

Concentration

1mg/mL

Dilution

IHC 1:100-200

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Molecular Weight

30kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

30kDa

Fragment

IgG

Subcellular Location

Cell membrane, Cell projection, Cytoplasm, Membrane

Other Product Names

KCNIP1, MGC9, MGC95, A type potassium channel modulatory protein 1

Gene ID (Human)

30820

Available Sizes

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