Methyl nicotinate

Methyl nicotinate (Nicotinic acid methyl ester) is an orally active vasodilator. Methyl nicotinate has analgesic activity. Methyl nicotinate causes local skin erythema when applied topically to the skin. Methyl nicotinate is used as an active ingredient in over-the-counter topical preparations for the study of muscle and joint pain[1][2][3][4].

Product Specifications

CAS Number

[93-60-7]

Product Name Alternative

Nicotinic acid methyl ester

UNSPSC

12352005

Hazard Statement

H315, H319, H335, H402

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/methyl-nicotinate.html

Concentration

10mM

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CN=C1)OC

Molecular Formula

C7H7NO2

Molecular Weight

137.14

Precautions

H315, H319, H335, H402

References & Citations

[1]Yarosh DB, rt al. Anti-inflammatory activity in skin by biomimetic of Evodia rutaecarpa extract from traditional Chinese medicine. J Dermatol Sci. 2006 Apr;42 (1) :13-21. |[2]Stringasci MD, et al. MAL-associated methyl nicotinate for topical PDT improvement. J Photochem Photobiol B. 2020 Dec;213:112071. |[3]Elawa S, et al. The microvascular response in the skin to topical application of methyl nicotinate: Effect of concentration and variation between skin sites. Microvasc Res. 2019 Jul;124:54-60. |[4] L. Johnston, et al. Muscle and joint pain: topical anti-inflammatories and analgesics: therapeutic. Professional Nursing Today, Volume 17, Issue 1, Jan 2013, p. 4-5.