IκB α Rabbit pAb
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines.
Product Specifications
Background
Product Name Alternative
I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody
UniProt
P25963
Swiss Prot
P25963
Reactivity
Human, Rat
Immunogen
Recombinant Protein
Clonality
Polyclonal
Source
Rabbit
Applications
WB, IHC
Concentration
1mg/mL
Dilution
WB 1:2,000-5,000 IHC 1:200-500
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
40kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
40kDa
Fragment
IgG
Subcellular Location
Cytoplasm, Nucleus
Other Product Names
I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody
Gene ID (Human)
4792
Available Sizes
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