Aromatase-IN-2
Aromatase-IN-2 is a potent aromatase inhibitor with an IC50 value of 1.5 µM[1].
Product Specifications
CAS Number
[121768-39-6]
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aromatase-in-2.html
Purity
99.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NCC1=CC=NC=C1)C2(C3)C[C@H](C4)C[C@@H]3C[C@H]4C2
Molecular Formula
C17H22N2O
Molecular Weight
270.37
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Chan FC, et al. 3- and 4-pyridylalkyl adamantanecarboxylates: inhibitors of human cytochrome P450 (17 alpha) (17 alpha-hydroxylase/C17,20-lyase) . Potential nonsteroidal agents for the treatment of prostatic cancer. J Med Chem. 1996 Aug 16;39 (17) :3319-23.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Aromatase/CYP19A1
Available Sizes
Curated Selection
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