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Vinculin Rabbit pAb

Vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane.

Product Specifications

Background

Vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane.

Synonyms

CMD1W antibody, CMH15 antibody, metavinculin antibody, MVCL antibody, VINC antibody

Gene ID

7414

UniProt

P18206

Cellular Locus

Cytoplasm,Cytoskeleton,Cell junction, Adherens junction

Host

Rabbit

Species Reactivity

Human,Rat,Mouse

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic Peptide

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC

Validated Applications

WB,IHC

Stability

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Concentration

1 mg/mL

Dilution

WB 1:1,000-2,000 IHC 1:200-500

Molecular Weight

130kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/EA043-1.pdf

Observed Molecular Weight

130 kDa

Subcellular Location

Cytoplasm, Cytoskeleton, Cell junction, Adherens junction

Other Product Names

CMD1W antibody, CMH15 antibody, metavinculin antibody, MVCL antibody, VINC antibody

Gene ID (Human)

7414

SwissProt (Human)

P18206

Available Sizes

Curated Selection

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