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Lamin B1 Rabbit pAb

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.

Product Specifications

Background

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.

Product Name Alternative

ADLD, LMB1, LMNB1, MGC111419, OTTHUMP00000159218

UniProt

P20700

Swiss Prot

P20700

Reactivity

Human, Rat, Mouse

Immunogen

Recombinant Protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB, IHC

Concentration

1mg/mL

Dilution

WB 1:1,000-3,000 IHC: 1:500-1,000

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Molecular Weight

68,45kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

68,45kDa

Fragment

IgG

Subcellular Location

Mitochondrion inner membrane

Other Product Names

ADLD, LMB1, LMNB1, MGC111419, OTTHUMP00000159218

Gene ID (Human)

4001

Available Sizes

Curated Selection

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