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FH/Fumarase Rabbit pAb

Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate in the mitochondria. Fumarase deficiency is caused by a mutation in the fumarase gene in humans. Fumarase deficiency is one of the few known deficiencies of the Krebs cycle or tricarboxylic acid cycle, the main enzymatic pathway of cellular aerobic respiration.

Product Specifications

Background

Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate in the mitochondria. Fumarase deficiency is caused by a mutation in the fumarase gene in humans. Fumarase deficiency is one of the few known deficiencies of the Krebs cycle or tricarboxylic acid cycle, the main enzymatic pathway of cellular aerobic respiration.

Product Name Alternative

Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1

UniProt

P07954

Swiss Prot

P07954

Reactivity

Human, Rat, Mouse

Immunogen

Recombinant Protein

Clonality

Polyclonal

Source

Rabbit

Applications

WB, IF

Concentration

1mg/mL

Dilution

WB 1:1,000

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Molecular Weight

50kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

50kDa

Fragment

IgG

Other Product Names

Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1

Gene ID (Human)

2271

Available Sizes

Curated Selection

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