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SAMD9 Recombinant Rabbit Monoclonal Antibody [PSH02-75]

Double-stranded nucleic acid binding that acts as a an antiviral factor by playing an essential role in the formation of cytoplasmic antiviral granules. May play a role in the inflammatory response to tissue injury and the control of extra-osseous calcification, acting as a downstream target of TNF-alpha signaling. Involved in the regulation of EGR1, in coordination with RGL2. May be involved in endosome fusion. Widely expressed. Very low levels are detected in skeletal muscle. Not detected in brain. Down-regulated in aggressive fibromatosis, as well as in breast and colon cancers. Up-regulated in fibroblasts from patients with normophosphatemic tumoral calcinosis (NFTC). Up-regulated by TNF-alpha through p38 MAPKs and NF-kappa-B. Up-regulated by osmotic shock. Induced by IFNG.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

C7orf5 antibody DRIF1 antibody expressed in aggressive fibromatosis antibody KIAA2004 antibody NFTC antibody OEF1 antibody OEF2 antibody SAM domain-containing protein 9 antibody SAMD9 antibody SAMD9_HUMAN antibody sterile alpha motif domain containing 9 antibody Sterile alpha motif domain-containing protein 9 antibody

Abbreviation

Sterile alpha motif domain-containing protein 9 SAM domain-containing protein 9 SAMD9 C7orf5, DRIF1, KIAA2004, OEF1

Swiss Prot

Q5K651 Human

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within human SMAD9 aa 1-250 / 1,589.

Isotype

IgG

Clone

PSH02-75

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

A549 cell lysate, HeLa cell lysate, A431 cell lysate, Raji cell lysate, HEK-293 cell lysate, MCF7 cell lysate, HepG2 cell lysate, HCT 116 cell lysate, U-87 MG cell lysate, A431, human skin tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:100 ;IHC-P: 1:200 ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 184 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

Curated Selection

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