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Acetyl P53 (K382) (1G7) Mouse mAb

P53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. Acetylation appears to play a positive role in the accumulation of p53 protein in stress response.

Product Specifications

Background

P53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. Acetylation appears to play a positive role in the accumulation of p53 protein in stress response.

Product Name Alternative

Cellular tumor antigen p53 antibody, Cys 51 stop antibody, Tp53 antibody, Tumor protein p53 antibody

UniProt

P04637

Swiss Prot

P04637

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic Peptide

Clonality

Monoclonal

Source

Mouse

Applications

IHC

Concentration

1mg/mL

Dilution

IHC 1:100-200

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Molecular Weight

53kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

53kDa

Fragment

IgG1

Subcellular Location

Cytoplasm, Cytoplasm. Nucleus

Other Product Names

Cellular tumor antigen p53 antibody, Cys 51 stop antibody, Tp53 antibody, Tumor protein p53 antibody

Gene ID (Human)

7157

Available Sizes

Curated Selection

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