Acetyl P53 (K382) (1G7) Mouse mAb
P53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. Acetylation appears to play a positive role in the accumulation of p53 protein in stress response.
Product Specifications
Background
Synonyms
Cellular tumor antigen p53 antibody, Cys 51 stop antibody, Tp53 antibody, Tumor protein p53 antibody
Gene ID
7157
UniProt
P04637
Cellular Locus
Cytoplasm,Cytoplasm. Nucleus
Host
Mouse
Species Reactivity
Human,Mouse,Rat
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Isotype
IgG1
Source
Mouse
Applications
IHC
Validated Applications
IHC
Stability
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Concentration
1 mg/mL
Dilution
IHC 1:100-200
Molecular Weight
53kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/mAb/EM1382-1.pdf
Observed Molecular Weight
53 kDa
Subcellular Location
Cytoplasm, Cytoplasm. Nucleus
Other Product Names
Cellular tumor antigen p53 antibody, Cys 51 stop antibody, Tp53 antibody, Tumor protein p53 antibody
Gene ID (Human)
7157
SwissProt (Human)
P04637
Available Sizes
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