ATG5 (3C7) Mouse mAb
Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.
Product Specifications
Background
Product Name Alternative
APG5, APG5L, ASP, Autophagy protein 5 antibody
UniProt
Q9H1Y0
Swiss Prot
Q9H1Y0
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Protein
Clonality
Monoclonal
Source
Mouse
Applications
WB, IHC
Concentration
1mg/mL
Dilution
WB 1:5,000-10,000 IHC 1:100-200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
55kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
55kDa
Fragment
IgG1
Subcellular Location
Cytoplasm, Membrane
Other Product Names
APG5, APG5L, ASP, Autophagy protein 5 antibody
Gene ID (Human)
9494
Available Sizes
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