NBR1 (7C3) Mouse mAb
NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.
Product Specifications
Background
Product Name Alternative
1A13B, MIG19, Nbr1
UniProt
Q14596
Swiss Prot
Q14596
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Protein
Clonality
Monoclonal
Source
Mouse
Applications
IHC
Concentration
1mg/mL
Dilution
IHC 1:100-200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
120kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
120kDa
Fragment
IgG1
Subcellular Location
Cytoplasm, Cytoplasmic vesicle, Lysosome
Other Product Names
1A13B, MIG19, Nbr1
Gene ID (Human)
4077
Available Sizes
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