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Collagen II (8F6) Mouse mAb

Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.

Product Specifications

Background

Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.

Product Name Alternative

Alpha 1 type II collagen , AOM, Col2a1 antibody

UniProt

P02458

Swiss Prot

P02458

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic Peptide

Clonality

Monoclonal

Source

Mouse

Applications

IHC

Concentration

1mg/mL

Dilution

IHC 1:100-200

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Molecular Weight

142kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

142kDa

Fragment

IgG1

Subcellular Location

Secreted, extracellular space, extracellular matrix

Other Product Names

Alpha 1 type II collagen , AOM, Col2a1 antibody

Gene ID (Human)

1280

Available Sizes

Curated Selection

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