Phospho-ERK 1/2 (Y205/222) (7A6) Mouse mAb
Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.
Product Specifications
Background
Product Name Alternative
MAPK, Mitogen-activated protein Kinase, PRKM2, MK01
UniProt
P27361/P28482
Swiss Prot
P27361/P28482
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Source
Mouse
Applications
IHC
Concentration
1mg/mL
Dilution
IHC 1:100-200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
44,42kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
44,42kDa
Fragment
IgG1
Subcellular Location
Nucleus
Other Product Names
MAPK, Mitogen-activated protein Kinase, PRKM2, MK01
Gene ID (Human)
5594/5595
Available Sizes
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