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ERK1/2 (1H4) Mouse mAb

Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.

Product Specifications

Background

Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.

Product Name Alternative

MAPK, Mitogen-activated protein Kinase, PRKM2, MK01

UniProt

P27361/P28482

Swiss Prot

P27361/P28482

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic Peptide

Clonality

Monoclonal

Source

Mouse

Applications

WB, IHC

Concentration

1mg/mL

Dilution

WB 1:1,000-2,000 IHC 1:100-200

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Molecular Weight

44,42kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

44,42kDa

Fragment

IgG1

Subcellular Location

Nucleus

Other Product Names

MAPK, Mitogen-activated protein Kinase, PRKM2, MK01

Gene ID (Human)

5594/5595

Available Sizes

Curated Selection

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