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ERK1 (5E9) Mouse mAb

Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.

Product Specifications

Background

Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.

Synonyms

MAPK, Mitogen-activated protein Kinase, PRKM2, MK01

Gene ID

5594

UniProt

P27361

Cellular Locus

Nucleus

Host

Mouse

Species Reactivity

Human,Rat,Mouse

Reactivity

Human, Rat, Mouse

Immunogen

Recombinant Protein

Clonality

Monoclonal

Isotype

IgG1

Source

Mouse

Applications

IHC

Validated Applications

IHC

Stability

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Concentration

1 mg/mL

Dilution

IHC 1:100-200

Molecular Weight

44kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/mAb/EM1323-1.pdf

Observed Molecular Weight

44 kDa

Subcellular Location

Nucleus

Other Product Names

MAPK, Mitogen-activated protein Kinase, PRKM2, MK01

Gene ID (Human)

5594

SwissProt (Human)

P27361

Available Sizes

Curated Selection

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