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ERK1 (5E9) Mouse mAb

Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.

Product Specifications

Background

Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.

UniProt

P27361

Swiss Prot

P27361

Reactivity

Human, Rat, Mouse

Immunogen

Recombinant Protein

Clonality

Monoclonal

Source

Mouse

Applications

IHC

Concentration

1mg/mL

Dilution

IHC 1:100-200

Molecular Weight

44kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/mAb/EM1323-1.pdf

Observed Molecular Weight

44kDa

Fragment

IgG1

Subcellular Location

Nucleus

Other Product Names

MAPK, Mitogen-activated protein Kinase, PRKM2, MK01

Gene ID (Human)

5594

Available Sizes

Curated Selection

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