Cystatin C (7F11) Mouse mAb
Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.
Product Specifications
Background
Product Name Alternative
AD8, Cystatin3, Gamma trace, HCCAA
UniProt
P01034
Swiss Prot
P01034
Reactivity
Human
Immunogen
Recombinant Protein
Clonality
Monoclonal
Source
Mouse
Applications
WB, IHC, ELISA
Concentration
1mg/mL
Dilution
WB 1:1,000-2,000 IHC 1:100-200 ELISA 1:10,000-20,000
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
14kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
14kDa
Fragment
IgG1
Subcellular Location
Secreted
Other Product Names
AD8, Cystatin3, Gamma trace, HCCAA
Gene ID (Human)
1471
Available Sizes
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