P44/42 MAPK (ERK1/2) Mouse mAb
Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.
Product Specifications
Background
UniProt
P27361/P28482
Swiss Prot
P27361/P28482
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Source
Mouse
Applications
WB, IHC
Concentration
1mg/mL
Dilution
WB 1:1,000-2,000 IHC 1:100-200
Molecular Weight
44,42kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/mAb/EM1221-1.pdf
Observed Molecular Weight
44,42kDa
Fragment
IgG1
Subcellular Location
Nucleus
Other Product Names
MAPK, Mitogen-activated protein Kinase, PRKM2, MK01
Gene ID (Human)
5594/5595
Available Sizes
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