P44/42 MAPK (ERK1/2) Mouse mAb
Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.
Product Specifications
Background
Synonyms
MAPK, Mitogen-activated protein Kinase, PRKM2, MK01
Gene ID
5594/5595
UniProt
P27361/P28482
Cellular Locus
Nucleus
Host
Mouse
Species Reactivity
Human,Rat,Mouse
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Isotype
IgG1
Source
Mouse
Applications
WB, IHC
Validated Applications
WB,IHC
Stability
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Concentration
1 mg/mL
Dilution
WB 1:1,000-2,000 IHC 1:100-200
Molecular Weight
44,42kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/mAb/EM1221-1.pdf
Observed Molecular Weight
44,42 kDa
Subcellular Location
Nucleus
Other Product Names
MAPK, Mitogen-activated protein Kinase, PRKM2, MK01
Gene ID (Human)
5594/5595
SwissProt (Human)
P27361/P28482
Available Sizes
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