TNF α Mouse mAb
TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein. It can cause cytolysis of certain tumor cell lines; it is involved in the induction of cachexia; it is a potent pyrogen, causing fever by direct action or by stimulation of interlerukin-1 secretion; it can stimulate cell proliferation and induce cell differentiation under certain conditions. .
Product Specifications
Background
Synonyms
APC1 antibody, DIF antibody, TNFSF2 antibody, Tumor necrosis factor alpha antibody
Gene ID
7124
UniProt
P01375
Cellular Locus
Secreted,Cell membrane
Host
Mouse
Species Reactivity
Human,Rat,Mouse
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Isotype
IgG1
Source
Mouse
Applications
WB, IHC
Validated Applications
WB,IHC
Stability
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Concentration
1 mg/mL
Dilution
WB 1:1,000-2,000 IHC 1:50
Molecular Weight
17,25kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/mAb/EM1197-1.pdf
Observed Molecular Weight
17,25 kDa
Subcellular Location
Secreted, Cell membrane
Other Product Names
APC1 antibody, DIF antibody, TNFSF2 antibody, Tumor necrosis factor alpha antibody
Gene ID (Human)
7124
SwissProt (Human)
P01375
Available Sizes
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