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TNF α Mouse mAb

TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein. It can cause cytolysis of certain tumor cell lines; it is involved in the induction of cachexia; it is a potent pyrogen, causing fever by direct action or by stimulation of interlerukin-1 secretion; it can stimulate cell proliferation and induce cell differentiation under certain conditions. .

Product Specifications

Background

TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein. It can cause cytolysis of certain tumor cell lines; it is involved in the induction of cachexia; it is a potent pyrogen, causing fever by direct action or by stimulation of interlerukin-1 secretion; it can stimulate cell proliferation and induce cell differentiation under certain conditions..

Product Name Alternative

APC1 antibody, DIF antibody, TNFSF2 antibody, Tumor necrosis factor alpha antibody

UniProt

P01375

Swiss Prot

P01375

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic Peptide

Clonality

Monoclonal

Source

Mouse

Applications

WB, IHC

Concentration

1mg/mL

Dilution

WB 1:1,000-2,000 IHC 1:50

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Molecular Weight

17,25kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

17,25kDa

Fragment

IgG1

Subcellular Location

Secreted, Cell membrane

Other Product Names

APC1 antibody, DIF antibody, TNFSF2 antibody, Tumor necrosis factor alpha antibody

Gene ID (Human)

7124

Available Sizes

Curated Selection

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