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Active Caspase 3 Mouse mAb

Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position.

Product Specifications

Background

Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position.

Synonyms

APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody

Gene ID

836

UniProt

P42574

Cellular Locus

Cytoplasm

Host

Mouse

Species Reactivity

Human,Rat,Mouse

Reactivity

Human, Rat, Mouse

Immunogen

Recombinant Protein

Clonality

Monoclonal

Isotype

IgG1

Source

Mouse

Applications

WB, IHC

Validated Applications

WB,IHC

Stability

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Concentration

1 mg/mL

Dilution

WB 1:500-1,000 IHC 1:100-200

Molecular Weight

17kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/mAb/EM1188-1.pdf

Observed Molecular Weight

17 kDa

Subcellular Location

Cytoplasm

Other Product Names

APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody

Gene ID (Human)

836

SwissProt (Human)

P42574

Available Sizes

Curated Selection

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