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Survivin Mouse mAb

Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death.

Product Specifications

Background

Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death.

UniProt

O15392

Swiss Prot

O15392

Reactivity

Human, Rat

Immunogen

Recombinant Protein

Clonality

Monoclonal

Source

Mouse

Applications

WB, IHC

Concentration

1mg/mL

Dilution

WB 1:1,000-2,000 IHC 1:200-500

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Molecular Weight

16kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

16kDa

Fragment

IgG1

Subcellular Location

Cytoplasm. Nucleus. Chromosome

Gene ID (Human)

332

Available Sizes

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