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Fibronectin Mouse mAb

Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen. Fibronectin exists as a protein dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms.

Product Specifications

Background

Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen.Fibronectin exists as a protein dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms.

Synonyms

CIG, Cold insoluble globulin, fibronectin 1, FN, fN1, FNZ, GFND, GFND2, UgI-Y3

Gene ID

2335

UniProt

P02751

Cellular Locus

Secreted, extracellular space, extracellular matrix

Host

Mouse

Species Reactivity

Human,Rat,Mouse

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic Peptide

Clonality

Monoclonal

Isotype

IgG1

Source

Mouse

Applications

WB, IHC

Validated Applications

WB,IHC

Stability

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Concentration

1 mg/mL

Dilution

WB 1:1,000-2,000 IHC 1:200-500

Molecular Weight

285kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/mAb/EM1137-1.pdf

Observed Molecular Weight

285 kDa

Subcellular Location

Secreted, extracellular space, extracellular matrix

Other Product Names

CIG, Cold insoluble globulin, fibronectin 1, FN, fN1, FNZ, GFND, GFND2, UgI-Y3

Gene ID (Human)

2335

SwissProt (Human)

P02751

Available Sizes

Curated Selection

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