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Fibronectin Mouse mAb

Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen. Fibronectin exists as a protein dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms.

Product Specifications

Background

Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen.Fibronectin exists as a protein dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms.

Product Name Alternative

CIG, Cold insoluble globulin, fibronectin 1, FN, fN1, FNZ, GFND, GFND2, UgI-Y3

UniProt

P02751

Swiss Prot

P02751

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic Peptide

Clonality

Monoclonal

Source

Mouse

Applications

WB, IHC

Concentration

1mg/mL

Dilution

WB 1:1,000-2,000 IHC 1:200-500

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Molecular Weight

285kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

285kDa

Fragment

IgG1

Subcellular Location

Secreted, extracellular space, extracellular matrix

Other Product Names

CIG, Cold insoluble globulin, fibronectin 1, FN, fN1, FNZ, GFND, GFND2, UgI-Y3

Gene ID (Human)

2335

Available Sizes

Curated Selection

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