CA IX/Carbonic Anhydrase IX Mouse mAb
The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. CAIX is considered to be one of the best cellular biomarkers of hypoxia. Furthermore, recent studies examining the association between CAIX levels and various clinicopathological outcomes suggest that CAIX expression may also be a valuable prognostic indicator for overall survival. Antibodies against CAIX serve as excellent excellent biomarkers of hypoxic regions in many solid tumors.
Product Specifications
Background
Product Name Alternative
UniProt
Q16790
Swiss Prot
Q16790
Reactivity
Human
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Source
Mouse
Applications
WB, IHC, IP
Concentration
1mg/mL
Dilution
WB 1:3,000 IP 1:200 IHC 1:100-200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
35-38kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
35-38kDa
Fragment
IgG1
Subcellular Location
Nucleus. Nucleus, nucleolus. Cell membrane. Cell projection, microvillus membrane.
Other Product Names
Gene ID (Human)
768
Available Sizes
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