FH/Fumarase Mouse mAb
Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety.
Product Specifications
Background
Product Name Alternative
Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1
UniProt
P07954
Swiss Prot
P07954
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Source
Mouse
Applications
WB, IF
Concentration
1mg/mL
Dilution
WB 1:3,000 IF 1:100-200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
50kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
50kDa
Fragment
IgG1
Subcellular Location
Cytoplasm and Mitochondrion.
Other Product Names
Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1
Gene ID (Human)
2271
Available Sizes
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