Myosin Heavy Chain Mouse mAb
Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies.
Product Specifications
Background
Product Name Alternative
UniProt
P12882
Swiss Prot
P12882
Reactivity
Human, Mouse, Rat, Fruit Fly, Nematode
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Source
Mouse
Applications
IHC, IF
Concentration
1mg/mL
Dilution
IHC 1:200 IF 1:100
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
220kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
220kDa
Fragment
IgG1
Subcellular Location
Cytoplasm, Thick filament
Other Product Names
Gene ID (Human)
4619
Available Sizes
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