CDX2 Mouse mAb
CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.
Product Specifications
Background
Product Name Alternative
Caudal Type Homeobox Transcription Factor 2 ; CDX3; Homeobox Protein CDX-2
UniProt
Q99626
Swiss Prot
Q99626
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Clonality
Monoclonal
Source
Mouse
Applications
WB, IHC
Concentration
1mg/mL
Dilution
WB 1:1,000 IHC 1:200
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
42kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
42kDa
Fragment
IgG1
Subcellular Location
Nucleus
Other Product Names
Caudal Type Homeobox Transcription Factor 2 ; CDX3; Homeobox Protein CDX-2
Gene ID (Human)
1045
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
DCC, ID (DCC, IGDCC1, Netrin receptor DCC, Colorectal cancer suppressor, Immunoglobulin superfamily DCC subclass member 1, Tumor suppressor protein DCC)
DCC, ID (DCC, IGDCC1, Netrin receptor DCC, Colorectal cancer suppressor, Immunoglobulin superfamily DCC subclass member 1, Tumor suppressor protein DCC)
