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CD20 Mouse mAb

CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca2+ channel subunit.

Product Specifications

Background

CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca2+ channel subunit.

Product Name Alternative

B lymphocyte antigen CD20, B1, Bp35, LEU 16, MS4A1, MS4A1, MS4A2, S7

UniProt

P11836

Swiss Prot

P11836

Reactivity

Human, Rat, Mouse

Immunogen

Synthetic Peptide

Clonality

Monoclonal

Source

Mouse

Applications

IHC

Concentration

1mg/mL

Dilution

IHC 1:200

Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Molecular Weight

35-37kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

35-37kDa

Fragment

IgG1

Subcellular Location

Membrane

Other Product Names

B lymphocyte antigen CD20, B1, Bp35, LEU 16, MS4A1, MS4A1, MS4A2, S7

Gene ID (Human)

931

Available Sizes

Curated Selection

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