Salvianolic acid C
Salvianolic acid C is a noncompetitive Cytochrome P4502C8 (CYP2C8) inhibitor and a moderate mixed inhibitor of Cytochrome P45022J2 (CYP2J2), with Kis of 4.82 μM and 5.75 μM for CYP2C8 and CYP2J2, respectively.
Product Specifications
CAS Number
[115841-09-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cytochrome P450
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Salvianolic_acid_C.html
Purity
99.94
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=C(O)C=CC(C[C@H](C(O)=O)OC(/C=C/C2=CC=C(O)C3=C2C=C(C4=CC(O)=C(O)C=C4)O3)=O)=C1
Molecular Formula
C26H20O10
Molecular Weight
492.43
Precautions
H302, H315, H319, H335
References & Citations
[1]Xu MJ, et al. Inhibitory Effects of Danshen components on CYP2C8 and CYP2J2. Chem Biol Interact. 2018 Jun 1;289:15-22.|[2]Song J, et al. Activation of Nrf2 signaling by salvianolic acid C attenuates NF‑κB mediated inflammatory response both in vivo and in vitro. Int Immunopharmacol. 2018 Oct;63:299-310.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CYP2
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
