Netupitant (Standard)
Netupitant (Standard) is the analytical standard of Netupitant. This product is intended for research and analytical applications. Netupitant (CID-6451149) is a highly potent, selective and orally active neurokinin-1 (NK1) receptor antagonist with a Ki of 0.95 nM for hNK1 in CHO cells. Netupitant has antiemetic affect[1][2][3].
Product Specifications
CAS Number
290297-26-6
Product Name Alternative
CID 6451149 (Standard)
UNSPSC
12352005
Target
Neurokinin Receptor; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/netupitant-standard.html
Smiles
CN1CCN(C2=CC(C3=C(C)C=CC=C3)=C(N(C)C(C(C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)(C)C)=O)C=N2)CC1
Molecular Formula
C30H32F6N4O
Molecular Weight
578.59
References & Citations
[1]Hoffmann T, et al. Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists. Bioorg Med Chem Lett. 2006 Mar 1;16 (5) :1362-5.|[2]Rizzi A, et al. In vitro and in vivo pharmacological characterization of the novel NK1 receptor selective antagonist Netupitant. Peptides. 2012 Sep;37 (1) :86-97.|[3]Stefano Palea, et al. Netupitant, a Potent and Highly Selective NK1 Receptor Antagonist, Alleviates Acetic Acid-Induced Bladder Overactivity in Anesthetized Guinea-Pigs. Front Pharmacol. 2016 Aug 4;7:234.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![CD34 Mouse Monoclonal Antibody [Clone ID: OTI8F11]](https://cdn.genprice.uk/products/937/68dd18ba061270361e908430/imageurl/cf808858.webp)
![ATG4A Recombinant Rabbit Monoclonal Antibody [JE32-31]](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81c74/imageurl/ha721010.webp)
HA721010 100 µL
ATG4A Recombinant Rabbit Monoclonal Antibody [JE32-31]
Sign In for Pricing
View Details 
![SSX5 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1D6]](https://cdn.genprice.uk/products/937/68dd1b6d061270361ea171e0/imageurl/ta504221bm.webp)
TA504221BM 100 µL
SSX5 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1D6]
Sign In for Pricing
View Details 