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(S) -Gebr32a

(S) -Gebr32a is a potent PDE4 inhibitor with IC50 values of 19.5, 2.1 µM for PDE4 cat; PDE4D3, respectively[1].

Product Specifications

CAS Number

3055162-32-5

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s-gebr32a.html

Smiles

FC(F)OC1=CC=C(C2=NN(C[C@@H](O)CN3CCOCC3)C=C2)C=C1OC4CCCC4

Molecular Formula

C22H29F2N3O4

Molecular Weight

437.48

References & Citations

[1]Cavalloro V, et al. Insight into GEBR-32a: Chiral Resolution, Absolute Configuration and Enantiopreference in PDE4D Inhibition. Molecules. 2020 Feb 19;25 (4) :935.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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