Human ADH5 Protein

<strong>Human ADH5 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2010901_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 42.3 kDa (1 mg/mL)_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> ADH-5 protein, ADH-5, ADH 5, ADHX protein, Alcohol dehydrogenase class-3 protein, ADH 5 protein, ADH5_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Mulderrig L, Garaycoechea JI, Tuong ZK, Millington CL, Dingler FA, Ferdinand JR, Gaul L, Tadross JA, Arends MJ, O'Rahilly S, Crossan GP, Clatworthy MR, Patel KJ. Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response Nature. 2021 Dec;600(7887):158-163._x000D_ 2: Ostberg LJ, Strömberg P, Hedberg JJ, Persson B, Höög JO. Analysis of mammalian alcohol dehydrogenase 5 (ADH5): characterisation of rat ADH5 with comparisons to the corresponding human variant Chem Biol Interact. 2013 Feb 25;202(1-3):97-103._x000D_ 3: Sebag SC, Zhang Z, Qian Q, Li M, Zhu Z, Harata M, Li W, Zingman LV, Liu L, Lira VA, Potthoff MJ, Bartelt A, Yang L. ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue Cell Rep. 2021 Nov 16;37(7):110003._x000D_ 4: Dingler FA, Wang M, Mu A, Millington CL, Oberbeck N, Watcham S, Pontel LB, Kamimae-Lanning AN, Langevin F, Nadler C, Cordell RL, Monks PS, Yu R, Wilson NK, Hira A, Yoshida K, Mori M, Okamoto Y, Okuno Y, Muramatsu H, Shiraishi Y, Kobayashi M, Moriguchi T, Osumi T, Kato M, Miyano S, Ito E, Kojima S, Yabe H, Yabe M, Matsuo K, Ogawa S, Göttgens B, Hodskinson MRG, Takata M, Patel KJ. Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans Mol Cell. 2020 Dec 17;80(6):996-1012.e9._x000D_ 5: Raffay TM, Bonilla-Fernandez K, Jafri A, Sopi RB, Smith LA, Cui F, O'Reilly M, Zhang R, Hodges CA, MacFarlane PM, Deutsch G, Martin RJ, Gaston B. Bronchopulmonary Dysplasia and Pulmonary Hypertension. The Role of Smooth Muscle adh5 Am J Respir Cell Mol Biol. 2021 Jul;65(1):70-80._x000D_ 6: Strömberg P, Höög JO. Human class V alcohol dehydrogenase (ADH5): A complex transcription unit generates C-terminal multiplicity Biochem Biophys Res Commun. 2000 Nov 30;278(3):544-9._x000D_ 7: Nakamura J, Holley DW, Kawamoto T, Bultman SJ. The failure of two major formaldehyde catabolism enzymes (ADH5 and ALDH2) leads to partial synthetic lethality in C57BL/6 mice Genes Environ. 2020 Jun 3;42:21._x000D_ 8: Mu A, Hira A, Niwa A, Osawa M, Yoshida K, Mori M, Okamoto Y, Inoue K, Kondo K, Kanemaki MT, Matsuda T, Ito E, Kojima S, Nakahata T, Ogawa S, Tanaka K, Matsuo K, Saito MK, Takata M. Analysis of disease model iPSCs derived from patients with a novel Fanconi anemia-like IBMFS ADH5/ALDH2 deficiency Blood. 2021 Apr 15;137(15):2021-2032._x000D_ 9: Hur MW, Edenberg HJ. Cloning and characterization of the ADH5 gene encoding human alcohol dehydrogenase 5, formaldehyde dehydrogenase Gene. 1992 Nov 16;121(2):305-11._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/11306061">10: Höög J, Brandt M, Hedberg JJ, Stromberg P. Mammalian alcohol dehydrogenase of higher classes: analyses of human ADH5 and rat ADH6 Chem Biol Interact. 2001 Jan 30;130-132(1-3):395-404. </a>_x000D_ _x000D_ <strong>Products Related to Human ADH5 Protein</strong><a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>