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Ethyl (E) -ferulate

Ethyl (E) -ferulate is an AMPK/Nrf2 signaling pathway activator that can reduce lipopolysaccharide -induced acute lung injury. Additionally, Ethyl (E) -ferulate exhibits free radical scavenging properties, providing anti-inflammatory, antioxidant, neuroprotective, and sunscreen effects. Ethyl (E) -ferulate holds promise for research in the fields of inflammation and neurodegenerative diseases[1][2][3].

Product Specifications

CAS Number

28028-62-8

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

AMPK; Keap1-Nrf2

Type

Reference compound

Related Pathways

Epigenetics; NF-κB; PI3K/Akt/mTOR

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ethyl-e-ferulate.html

Smiles

CCOC(/C=C/C1=CC(OC)=C(C=C1)O)=O

Molecular Formula

C12H14O4

Molecular Weight

222.24

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Wu YX, et al. Ethyl ferulate protects against lipopolysaccharide-induced acute lung injury by activating AMPK/Nrf2 signaling pathway. Acta Pharmacol Sin. 2021 Dec;42 (12) :2069-2081.|[2]Nazaré A C, et al. Ethyl ferulate, a component with anti-inflammatory properties for emulsion-based creams[J]. Molecules, 2014, 19 (6) : 8124-8139.|[3]Cunha FVM, et al. Systematic review and technological prospection: ethyl ferulate, a phenylpropanoid with antioxidant and neuroprotective actions. Expert Opin Ther Pat. 2019 Feb;29 (2) :73-83.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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