SRI-37330 (hydrochloride)
SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. SRI-37330 hydrochloride inhibits glucagon secretion and function, reduces hepatic glucose production and reverses hepatic steatosis. SRI-37330 hydrochloride can be used for type 2 diabetes research[1].
Product Specifications
CAS Number
[2322245-49-6]
UNSPSC
12352005
Target
Arrestin
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sri-37330-hydrochloride.html
Purity
99.72
Solubility
DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=S(NCC1CN(CCC1)C2=C3C=C(C(F)(F)F)C=CC3=NC=N2)(C)=O.Cl
Molecular Formula
C16H20ClF3N4O2S
Molecular Weight
424.87
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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