Pivmecillinam (hydrochloride)

Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic.

Product Specifications

CAS Number

[32887-03-9]

Product Name Alternative

FL-1039 hydrochloride

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Pivmecillinam-hydrochloride.html

Concentration

10mM

Purity

99.19

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2/N=C/N3CCCCCC3)N1C2=O)OCOC(C(C)(C)C)=O.[H]Cl

Molecular Formula

C21H34ClN3O5S

Molecular Weight

476.03

Precautions

H302, H315, H319, H335

References & Citations

[1]Nicolle LE. Pivmecillinam in the treatment of urinary tract infections. J Antimicrob Chemother. 2000 Aug;46 Suppl A:35-39.|[2]Graninger W. Pivmecillinam--therapy of choice for lower urinary tract infection. Int J Antimicrob Agents. 2003 Oct;22 Suppl 2:73-8.|[3]Holme E, et al. Carnitine deficiency induced by pivampicillin and pivmecillinam therapy. Lancet. 1989 Aug 26;2 (8661) :469-73.|[4]Zykov IN, et al. Efficacy of mecillinam against clinical multidrug-resistant Escherichia coli in a murine urinary tract infection model. Int J Antimicrob Agents. 2020 Feb;55 (2) :105851.