ARI-3144
ARI-3144 is an excellent and specific substrate for fibroblast activation protein (FAP). ARI-3144 is usually coupled with the fluorophore 7-Amino-4-methylcoumarin (AMC) for detection and quantification of FAP[1].
Product Specifications
CAS Number
1426305-25-0
UNSPSC
12352005
Target
FAP
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ari-3144.html
Purity
99.72
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1[C@@H](CCC1)C(NC2=CC=C(C(C)=CC(O3)=O)C3=C2)=O)[C@@H](C)NC(C4=CC=NC5=C4C=CC=C5)=O
Molecular Formula
C28H26N4O5
Molecular Weight
498.53
References & Citations
[1]Keane FM, et al. Quantitation of fibroblast activation protein (FAP) -specific protease activity in mouse, baboon and human fluids and organs. FEBS Open Bio. 2013 Dec 8;4:43-54.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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