Human Complement C4 Deficient Heparin Plasma

<strong>Human Complement C4 Deficient Heparin Plasma </strong>_x000D_ <strong>Catalog number:</strong> B2015074_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mL_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Plasma_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20° C_x000D_ <strong>Keywords:</strong> Complement Component 4, Complement Component IV, C4, CIV, Acidic C4, Acidic Complement C4, Basic C4, C3 and PZP-like alpha-2-Macroglobulin Domain-containing Protein 2, C4 Anaphylatoxin_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Burge J, Nicholson-Weller A, Austen KF. Isolation of C4-binding protein from guinea pig plasma and demonstration of its function as a control protein of the classical complement pathway C3 convertase J Immunol. 1981 Jan;126(1):232-5._x000D_ 2: Majluf-Cruz A, Nieto-Martínez S. Long-term follow up analysis of nadroparin for hereditary angioedema. A preliminary report Int Immunopharmacol. 2011 Aug;11(8):1127-32._x000D_ 3: Thorisdottir H, Evans JA, Schwartz HJ, Comp P, Haluschak J, Ratnoff OD. Some clotting factors in plasma during danazol therapy: free and total protein S, but not C4b-binding protein, are elevated by danazol therapy J Lab Clin Med. 1992 Jun;119(6):698-701._x000D_ 4: Hopen G, Glette J, Matre R. Mechanisms of decreased leucocyte adhesiveness and migration in plasma from patients with IgG myelomatosis Scand J Haematol. 1984 Jan;32(1):88-94._x000D_ 5: Lundtoft C, Sjöwall C, Rantapää-Dahlqvist S, Bengtsson AA, Jönsen A, Pucholt P, Wu YL, Lundström E, Eloranta ML, Gunnarsson I, Baecklund E, Jonsson R, Hammenfors D, Forsblad-d'Elia H, Eriksson P, Mandl T, Bucher S, Norheim KB, Auglaend Johnsen SJ, Omdal R, Kvarnström M, Wahren-Herlenius M, Truedsson L, Nilsson B, Kozyrev SV, Bianchi M, Lindblad-Toh K; DISSECT consortium, the ImmunoArray consortium; Yu CY, Nordmark G, Sandling JK, Svenungsson E, Leonard D, Rönnblom L. Strong Association of Combined Genetic Deficiencies in the Classical Complement Pathway With Risk of Systemic Lupus Erythematosus and Primary Sjögren's Syndrome Arthritis Rheumatol. 2022 Nov;74(11):1842-1850._x000D_ 6: Kaplan AP, Joseph K. Complement, Kinins, and Hereditary Angioedema: Mechanisms of Plasma Instability when C1 Inhibitor is Absent Clin Rev Allergy Immunol. 2016 Oct;51(2):207-15._x000D_ 7: Davis AE 3rd. The pathophysiology of hereditary angioedema Clin Immunol. 2005 Jan;114(1):3-9._x000D_ 8: Stites E, Renner B, Laskowski J, Le Quintrec M, You Z, Freed B, Cooper J, Jalal D, Thurman JM. Complement fragments are biomarkers of antibody-mediated endothelial injury Mol Immunol. 2020 Feb;118:142-152._x000D_ 9: Aabom A, Bygum A, Koch C. Complement factor C4 activation in patients with hereditary angioedema Clin Biochem. 2017 Oct;50(15):816-821._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/2971510">10: Dalmasso AP. Complement in the pathophysiology and diagnosis of human diseases Crit Rev Clin Lab Sci. 1986;24(2):123-83. </a>_x000D_ _x000D_ <strong>Products Related to Human Complement C4 Deficient Heparin Plasma can be found at</strong> <a href="https://moleculardepot.com/product-category/Biofluids/"> Biofluids</a>