PACAP27 (Human, 1-27 Amide)

<strong>PACAP27 (Human, 1-27 Amide)</strong> <strong>Catalog number:</strong> MDP0616 <strong>CAS Number: </strong>131602-53-4 <strong>Sequence: </strong>His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2 <strong>Amount:</strong> 500 ug <strong>Molecular Weight:</strong> 3147.6 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Ghanizada H, Al-Karagholi MA, Arngrim N, Olesen J, Ashina M. PACAP27 induces migraine-like attacks in migraine patients Cephalalgia. 2020 Jan;40(1):57-67. 2: Velasco ER, Florido A, Flores Á, Senabre E, Gomez-Gomez A, Torres A, Roca A, Norrholm S, Newman EL, Das P, Ross RA, Lori A, Pozo OJ, Ressler KJ, Garcia-Esteve LL, Jovanovic T, Andero R. PACAP-PAC1R modulates fear extinction via the ventromedial hypothalamus Nat Commun. 2022 Jul 28;13(1):4374. 3: Yan BM, Gibson Depoy EM, Ahmad A, Nahas SJ. Biomarkers in Migraine Neurol India. 2021 Mar-Apr;69(Supplement):S17-S24. 4: Ashina H, Guo S, Vollesen ALH, Ashina M. PACAP38 in human models of primary headaches J Headache Pain. 2017 Nov 23;18(1):110. 5: Liu J, Wang G, Dan Y, Liu X. CGRP and PACAP-38 play an important role in diagnosing pediatric migraine J Headache Pain. 2022 Jun 13;23(1):68. 6: Rozzi SJ, Borelli G, Ryan K, Steiner JP, Reglodi D, Mocchetti I, Avdoshina V. PACAP27 is protective against tat-induced neurotoxicity J Mol Neurosci. 2014 Nov;54(3):485-93. 7: Moody TW, Jensen RT. Pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal peptide (Part 2): biology and clinical importance in central nervous system and inflammatory disorders Curr Opin Endocrinol Diabetes Obes. 2021 Apr 1;28(2):206-213. 8: Patko E, Szabo E, Toth D, Tornoczky T, Bosnyak I, Vaczy A, Atlasz T, Reglodi D. Distribution of PACAP and PAC1 Receptor in the Human Eye J Mol Neurosci. 2022 Nov;72(11):2176-2187. 9: Tassorelli C, De Icco R. Getting closer to a cure for migraine Nat Rev Neurol. 2019 Feb;15(2):64-65. <a href="https://pubmed.ncbi.nlm.nih.gov/19859678">10: Fahrenkrug J. VIP and PACAP Results Probl Cell Differ. 2010;50:221-34. </a> <br><strong>Products Related to PACAP27 (Human, 1-27 Amide) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>