ITGA2B (light chain form 1, Cleaved-Gln891) rabbit pAb
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],
Product Specifications
Background
UniProt
P08514
Swiss Prot
P08514
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human ITGA2B (light chain form 1, Cleaved-Gln891)
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
16 110kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
16 110kD
Fragment
IgG
Subcellular Location
Membrane; Single-pass type I membrane protein.
Other Product Names
Gene ID (Human)
3674
Available Sizes
Frequently Asked Questions
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