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Boc-Val-Leu-Lys-AMC

Boc-Val-Leu-Lys-AMC is a sensitive, fluorogenic, and specific substrate of plasmin, as well as acrosin from the ascidian Halocynthia roretzi, porcine calpain isozymes I and II, and papain[1][2][3][4].

Product Specifications

CAS Number

73554-84-4

UNSPSC

12352209

Target

Ser/Thr Protease

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/boc-val-leu-lys-amc.html

Purity

98.93

Solubility

10 mM in DMSO

Smiles

CC(C1=CC=C(NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC(OC(C)(C)C)=O)=O)=O)=O)C=C1O2)=CC2=O

Molecular Formula

C32H49N5O7

Molecular Weight

615.76

References & Citations

[1]T Sasaki, et al. Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates. J Biol Chem. 1984 Oct 25;259 (20) :12489-94.|[2]H Kato, et al. New fluorogenic peptide substrates for plasmin. J Biochem. 1980 Jul;88 (1) :183-90.|[3]R E Smith, et al. Direct photometric or fluorometric assay of proteinases using substrates containing 7-amino-4-trifluoromethylcoumarin. Thromb Res. 1980 Feb;17 (3-4) :393-402.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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