Boc-Val-Leu-Lys-AMC
Boc-Val-Leu-Lys-AMC is a sensitive, fluorogenic, and specific substrate of plasmin, as well as acrosin from the ascidian Halocynthia roretzi, porcine calpain isozymes I and II, and papain[1][2][3][4].
Product Specifications
CAS Number
73554-84-4
UNSPSC
12352209
Target
Ser/Thr Protease
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/boc-val-leu-lys-amc.html
Purity
98.93
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC(OC(C)(C)C)=O)=O)=O)=O)C=C1O2)=CC2=O
Molecular Formula
C32H49N5O7
Molecular Weight
615.76
References & Citations
[1]T Sasaki, et al. Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates. J Biol Chem. 1984 Oct 25;259 (20) :12489-94.|[2]H Kato, et al. New fluorogenic peptide substrates for plasmin. J Biochem. 1980 Jul;88 (1) :183-90.|[3]R E Smith, et al. Direct photometric or fluorometric assay of proteinases using substrates containing 7-amino-4-trifluoromethylcoumarin. Thromb Res. 1980 Feb;17 (3-4) :393-402.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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