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[cPP1-7, NPY19-23, Ala31, Aib32, Gln34]-hPancreatic polypeptide (TFA)

[cPP1-7, NPY19-23, Ala31, Aib32, Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist with an IC50 of 0.24 nM for binding to the hY5 receptor. [cPP1-7, NPY19-23, Ala31, Aib32, Gln34]-hPancreatic Polypeptide induces a high amount of food intake[1].

Product Specifications

UNSPSC

12352209

Target

Neuropeptide Y Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cpp1-7-npy19-23-ala31-aib32-gln34-hpancreatic-polypeptide-tfa.html

Solubility

H2O

Smiles

O=C(CN)N1[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N3[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NC(C)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC5=CC=C(O)C=C5)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)C)=O)C)=O)CCSC)=O)CC(N)=O)=O)[C@H](CC)C)=O)CC6=CC=C(O)C=C6)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CC(C)C)=O)C)=O)CO)=O)CC7=CC=C(O)C=C7)=O)CC8=CC=C(O)C=C8)=O)CCCNC(N)=N)=O)C)=O)CCSC)=O)CCC(N)=O)=O)CCC(O)=O)=O)CCC4)=O)[C@@H](C)O)=O)C)=O)CC(N)=O)=O)CC(O)=O)=O)=O)CCC3)=O)CC9=CC=C(O)C=C9)=O)[C@@H](C)O)=O)CCC2)=O)CCC(N)=O)=O)CO)=O)CCC1.O=C(O)C(F)(F)F

Molecular Formula

C185H282F3N57O56S2

Molecular Weight

4321.68

References & Citations

5

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

NPY Y1 receptor; NPY Y2 receptor; NPY Y4 receptor; NPY Y5 receptor

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